Functional genomics reveals the mechanism of hypoxic adaptation in nontuberculous mycobacteria 

Tateishi Yoshitaka, Ozeki Yuriko, Nishiyama Akihito, Morishige Yuta, Minato Yusuke, Baughn Anthony D, Matsumoto Sohkichi 

eLife, 2024, 13:RP99426

 

Construction of knockout mutants in Mycobacterium intracellulare ATCC13950 strain using a thermosensitive plasmid containing negative selection marker rpsL.

Tateishi Y, Nishiyama A, Ozeki Y, Matsumoto S.

Microbiol Immunol. 2024 Oct;68(10):339-347.

 

Exploring Indonesian actinomycete extracts for anti-tubercular compounds: Integrating inhibition assessment, genomic analysis, and prediction of its target by molecular docking.

Nurkanto A, Masrukhin, Erdian Tampubolon JC, Ewaldo MF, Putri AL, Ratnakomala S, Setiawan R, Fathoni A, Palupi KD, Rahmawati Y, Waluyo D, Prabandari EE, Pujiyanto S, Sumii Y, Agusta A, Shibata N, Matsumoto S, Nozaki T.

 Heliyon. 2024 Aug 4;10(15):e35648.

 

Recombinant Mycobacterial DNA-binding Protein 1 with post-translational modifications boosts IFN-gamma production from BCG-vaccinated individuals’ blood cells in combination with CpG-DNA. 

Yuriko Ozeki, Akira Yokoyama, Akihito Nishiyama, Yutaka Yoshida, Yukiko Ohara, Tsukasa Mashima, Chikako Tomiyama, Amina K. Shaban, Atsuki Takeishi, Mayuko Osada-Oka, Takehiro Yamaguchi, Yoshitaka Tateishi, Jun-ichi Maeyama, Mariko Hakamata, Hiroshi Moro, Toshiaki Kikuchi, Daisuke Hayashi, Fumiko Suzuki, Toshiko Yamamoto, Sumiko Iho, Masato Katahira, Saburo Yamamoto, & Sohkichi Matsumoto

Scientific Reports, 2024 Apr 21;14(1):9141. doi: 10.1038/s41598-024-58836-8.

 

Evaluation of cytokine profiles related to Mycobacterium tuberculosis latent antigens using a whole-blood assay in the Philippines.

Ikkoh Yasuda, Naomi Ruth D. Saludar, Ana Ria Sayo, Shuichi Suzuki, Akira Yokoyama, Yuriko Ozeki, Haruka Kobayashi, Akihito Nishiyama, Sohkichi Matsumoto, Sharon Cox, Takeshi Tanaka & Yoshiro Yamashita

Frontiers in Immunology, Volume 15 - 2024 | https://doi.org/10.3389/fimmu.2024.1330796

 

Association between diet quality and risk of stunting among school-aged children in Schistosoma mansoni endemic area of western Kenya: a cross-sectional study.

Kishino M, Hida A, Chadeka EA, Inoue M, Osada-Oka M, Matsumoto S, Njenga SM, Hamano S, Nagi S.

Trop Med Health. 2024 Jan 17;52(1):12. doi: 10.1186/s41182-023-00566-0.

 

Genetic engineering employing MPB70 and its promoter enables efficient secretion and expression of foreign antigen in bacillus Calmette Guérin (BCG) Tokyo.

Takeishi A, Shaban AK, Kakihana T, Takihara H, Okuda S, Osada H, Suameitria Dewi DNS, Ozeki Y, Yoshida Y, Nishiyama A, Tateishi Y, Aizu Y, Chuma Y, Onishi K, Hayashi D, Yamamoto S, Mukai T, Ato M, Thai DH, Nhi HTT, Shirai T, Shibata S, Obata F, Fujii J, Yamayoshi S, Kiso M, Matsumoto S.

Microbiol Immunol. 2024 Jan 31. doi: 10.1111/1348-0421.13116. 

  

Dynamic action of an intrinsically disordered protein in DNA compaction that induces mycobacterial dormancy.

 Akihito Nishiyama,  Masahiro Shimizu,  Tomoyuki Narita,  Noriyuki Kodera,  Yuriko Ozeki, Akira Yokoyama,  Kouta Mayanagi,  Takehiro

Yamaguchi,  Mariko Hakamata, Amina Kaboso Shaban,  Yoshitaka Tateishi,  Kosuke Ito,  Sohkichi Matsumoto.  Nucleic Acid Res., Volume

52,Issue 2, 25 January 2024, Pages816–830, https://doi.org/10.1093/nar/gkad1149

 ↑

2月14日、プレスリリースされました。

 

松本　壮吉、マイコバクテリウム属（抗酸菌）。標準微生物学 第15版。2024年、錫谷 達夫、松本 哲哉　編。医学書院、ISBN-13: 978-4-260-05344-0

 

 

 

Association between diet quality and risk of stunting among school-aged children in Schistosoma mansoni endemic area of Western Kenya:

A cross-sectional study. 

Madoka Kishino; Azumi Hida; Evans Asena Chadeka; Manabu Inoue; Mayuko Osada-Oka; Sohkichi Matsumoto; Sammy M. Njenga;Shinjiro Hamano; Sachiyo Nagi.  Tropical Medicine and Health,2024 Jan 17;52(1):12. doi: 10.1186/s41182-023-00566-0.

 

Shaban, A. K., G. Gebretsadik, M. Hakamata, H. Takihara, E. Inouchi, A. Nishiyama, Y. Ozeki, Y. Tateishi, Y. Nishiuchi, T. Yamaguchi, N. Ohara, S. Okuda, and S. Matsumoto. 2023. Mycobacterial DNA-binding protein 1 is critical for BCG survival in stressful environments and simultaneously regulates gene expression. Sci Rep 13: 14157.

  

Yoshida, Y., A. Nishiyama, D. N. S. Suameitria Dewi, T. Yamazaki, A. Yokoyama, D. Kobayashi, H. Kondo, Y. Ozeki, and S. Matsumoto. 2023. Limited proteolysis of mycobacterial DNA-binding protein 1 with an extended, lysine-rich, intrinsically disordered region to unveil posttranslational modifications. Biochem Biophys Res Commun 681: 111-119.

 

Yamashita, Y., I. Yasuda, T. Tanaka, T. Ikeda, M. Terada, M. Takaki, Y. Tsuchihashi, N. Asoh, Y. Ohara, S. Enany, H. Kobayashi, S. Matsumoto, and K. Morimoto. 2023. Antigen-specific cytokine profiles for pulmonary Mycobacterium avium complex disease stage diagnosis. Front Immunol 14: 1222428.

 

Tateishi, Y., Y. Ozeki, A. Nishiyama, M. Miki, R. Maekura, H. Kida, and S. Matsumoto. 2023. Virulence of Mycobacterium intracellulare clinical strains in a mouse model of lung infection - role of neutrophilic inflammation in disease severity. BMC Microbiol 23: 94.

 

Setyawan, M. F., N. M. Mertaniasih, S. Soedarsono, Z. Nuha, Y. Maladan, and S. Matsumoto. 2023. Mycobacterium tuberculosis - atpE gene profile of bedaquiline-treated pulmonary tuberculosis patients at the referral hospital Dr. Soetomo, Indonesia. Int J Mycobacteriol 12: 122-128.

 

Dewi, D., N. M. Mertaniasih, Soedarsono, K. Hagino, T. Yamazaki, Y. Ozeki, W. T. Artama, H. Kobayashi, E. Inouchi, Y. Yoshida, S. Ishikawa, A. K. Shaban, Y. Tateishi, A. Nishiyama, M. Ato, and S. Matsumoto. 2023. Antibodies against native proteins of Mycobacterium tuberculosis can detect pulmonary tuberculosis patients. Sci Rep 13: 12685.

 

総説

松本　壮吉。人の長寿と長生きの抗酸菌;　抗酸菌がゆっくりと生きて頻繁に眠るしくみから、薬剤開発への展開を考える。

第96回日本ハンセン病学会シンポジウム、ミニレビュー、第 92 巻 2 号(2023 年 8 月) P41-46

 

著書

立石　善隆、松本　壮吉。マイコバクテリウム属細菌（抗酸菌）による疾病とバイオフィルム形成。野村　暢彦　監修、

バイオフィルム革新的制御技術、124-132、NTSinc, 東京、ISBN 978-4-86043-0 C3045, 2023

 

 

Samukawa, N., T. Yamaguchi, Y. Ozeki, S. Matsumoto, M. Igarashi, N. Kinoshita, M. Hatano, K. Tokudome, S. Matsunaga, and S. Tomita. 2022. An efficient CRISPR interference-based prediction method for synergistic/additive effects of novel combinations of anti-tuberculosis drugs. Microbiology (Reading) 168. DOI: 10.1099/mic.0.001285

 

Asamizu, S., S. Ijichi, S. Hoshino, H. Jo, H. Takahashi, Y. Itoh, S. Matsumoto, and H. Onaka. 2022. Stable Isotope-Guided Metabolomics Reveals Polar-Functionalized Fatty-Acylated RiPPs from Streptomyces. ACS Chem Biol 17: 2936-2944. DOI: 10.1021/acschembio.2c00601

 

Geberetsadik, G., A. Inaizumi, A. Nishiyama, T. Yamaguchi, H. Hamamoto, S. Panthee, A. Tamaru, M. Hayatsu, Y. Mizutani, S. A. Kaboso, M. Hakamata, A. Ilinov, Y. Ozeki, Y. Tateishi, K. Sekimizu, and S. Matsumoto. 2022. Lysocin E Targeting Menaquinone in the Membrane of Mycobacterium tuberculosis Is a Promising Lead Compound for Antituberculosis Drugs. Antimicrob Agents Chemother 66: e0017122. DOI: 10.1128/aac.00171-22

 

Ryoji Maekura , Keisuke Miki, Yoshitaka Tateishi, Sohkichi Matsumoto, Seigo Kitada, Mari Miki, Hiroshi Kida

Long-Term Prognosis and Antimycobacterial Glycolipid Antibody as Biomarker in Mycobacterium avium-intracellulare Complex Pulmonary Disease

Microbiol Spectr. 2022 Jun 29;10(3):e0053022. doi: 10.1128/spectrum.

 

Satoshi Ishikawa, Yuriko Ozeki, Satomi Suga, Yasuhiko Mukai, Haruka Kobayashi, Erina Inouchi, Shaban A. Kaboso, Gebremichal Gebretsadik, Desak Nyoman Surya Suameitria Dewi, Akihito Nishiyama, Yoshitaka Tateishi, Hayato Takihara, Shujiro Okuda, Shiomi Yoshida, Naoaki Misawa, and Sohkichi Matsumoto

Monitoring IgG against Mycobacterium tuberculosis proteins in an Asian elephant cured of tuberculosis that developed from long-term latency

Scientific Reports. 2022 Mar 12;12(1):4310. doi: 10.1038/s41598-022-08228-7.

 

Yukiko Nishiuchi, Yoshitaka Tateishi, Hiroshi Hirano, Yuriko Ozeki, Takehiro Yamaguchi, Mari Miki, Seigo Kitada, Fumito Maruyama, and Sohkichi Matsumoto

Direct attachment with erythrocytes augments extracellular growth of pathogenic mycobacteria

2022 Apr 27;10(2):e0245421. doi: 10.1128/spectrum.02454-21.

 

Tohru Abe, Mariko Hakamata, Akihito Nishiyama, Yoshitaka Tateishi, Sohkichi Matsumoto, Hisashi Hemmi, Daijiro Ueda, Tsutomu Sato

Identification and functional analysis of a new type of Z, E-mixed prenyl reductase from mycobacteria

The FEBS Journal 2022 Feb 24. doi: 10.1111/febs.16412. 

 

Tomomi Kurane, Tetsuro Matsunaga, Tomoaki Ida, Kazuko Sawada, Akira Nishimura, Masayuki Fukui, Masayuki Umemura, Masaaki Nakayama, Naoya Ohara, Sohkichi Matsumoto, Takaaki Akaike, Goro Matsuzaki , Giichi Takaesu 

GRIM-19 is a target of mycobacterial Zn 2+ metalloprotease 1 and indispensable for NLRP3 inflammasome activation

The FASEB Journal 2022 Jan;36(1):e22096. doi: 10.1096/fj.202101074RR.

 

 著書

Nishiyama A and Matsumoto S.  Bacterial factors regulating M. tuberculosis infection and persistence.  Yamamoto S, Maeyama J, and Takii T editors.  BCG vaccine and adjuvant, Japan anti-tuberculosis association, Tokyo, 212-229, 2022

 

Ozeki Y, Niki M and Matsumoto S.  Host and bacterial factors that regulate Mycobacterium tuberculosis infection and persistence.  Yamamoto S, Maeyama J, and Takii T editors.  BCG vaccine and adjuvant, Japan anti-tuberculosis association, Tokyo, 235-240, 2022

 

Oh S, Libardo MDJ, Azeeza S, Pauly GT, Roma JSO, Sajid A, Tateishi Y, Duncombe C, Goodwin M, Ioerger TR, Wyatt PG, Ray PC, Gray DW, Boshoff HIM, Barry CE 3rd. Structure-activity relationships of pyrazolo[1,5-a]pyrimidin-7(4H)-ones as antitubercular agents. 

ACS Infect Dis. 2021 Feb 12;7(2):479-492. doi: 10.1021/acsinfecdis.0c00851. Epub 2021 Jan 6. PMID: 33405882.

 

The espD full gene as a potential biomarker in active pulmonary tuberculosis.

Mertaniasih NM, Surya Suameitria Dewi DN, Soedarsono S, Kurniati A, Rohman A, Nuha Z, Matsumoto S.

Int J Mycobacteriol. 2021 Oct-Dec;10(4):421-427.

 

Microbiome in sputum as a potential biomarker of chronicity in pulmonary resistant to rifampicin-tuberculosis and multidrug-resistant-tuberculosis patients.

Wiqoyah N, Mertaniasih NM, Artama WT, Matsumoto S.

Int J Mycobacteriol. 2021 Jul-Sep;10(3):260-267.

 

 Extracellular DNA of slow growers of mycobacteria and its contribution to biofilm formation and drug tolerance.

Aleksandr Ilinov, Akihito Nishiyama, Hiroki Namba, Yukari Fukushima, Hayato Takihara, Chie Nakajima, Anna Savitskaya, Yuri Vinnik, Gebremichal Gebretsadik, Mariko Hakamata, Yuriko Ozeki, Yoshitaka Tateishi, Shujiro Okuda, Yasuhiko Suzuki, & Sohkichi Matsumoto

Sci Rep. 2021 May 26;11(1):10953.

 

Tateishi, Y., Y. Ozeki, A. Nishiyama, M. Miki, R. Maekura, Y. Fukushima, C. Nakajima, Y. Suzuki, and S. Matsumoto. 2021. Comparative genomic analysis of Mycobacterium intracellulare: Implications for clinical taxonomic classification in pulmonary Mycobacterium avium-intracellulare complex disease. BMC Microbiology In press.

 

Maeyama, J. I., S. Iho, F. Suzuki, D. Hayashi, T. Yamamoto, T. Yamazaki, Y. Goto, Y. Ozeki, S. Matsumoto, and S. Yamamoto. 2021. Evaluation of a booster tuberculosis vaccine containing mycobacterial DNA-binding protein 1 and CpG oligodeoxynucleotide G9.1 using a Guinea pig model that elicits immunity to Bacillus Calmette-Guérin. Tuberculosis (Edinburgh, Scotland) 128: 102067.

 

Enany, S., M. Ato, and S. Matsumoto. 2021. Differential Protein Expression in Exponential and Stationary Growth Phases of Mycobacterium avium subsp. hominissuis 104. Molecules 26.

 

著書

標準微生物学　第14版（医学書院）2021。神谷　茂　監修、錫谷 達夫 / 松本 哲哉　編集。｢マイコバクテリウム属 (抗酸菌)｣、松本　壮吉。

 

竹石　惇樹、松本　壮吉、藤井　雅寛。創薬研究者がこれだけは知っておきたい最新のウイルス学。｢BCGのウイルス感染症に対する効果と組換えBCG｣　技術情報研協会、東京。534-543、2021

 

総説

竹石 惇樹、長田 秀和、松本 壮吉。

 

BCGベクターワクチン設計のサイエンス。医学のあゆみ。279号、No 10、p1041-1046、2021

 

Hakamata, M.*, H. Takihara, T. Iwamoto, A. Tamaru, A. Hashimoto, T. Tanaka, S. A. Kaboso, G. Gebretsadik, A. Ilinov, A. Yokoyama, Y. Ozeki, A. Nishiyama, Y. Tateishi, H. Moro, T. Kikuchi, S. Okuda, and S. Matsumoto. 2020. Higher genome mutation rates of Beijing lineage of Mycobacterium tuberculosis during human infection. Sci Rep 10: 17997.

 

Tateishi, Y.*, Y. Minato, A. D. Baughn, H. Ohnishi, A. Nishiyama, Y. Ozeki, and S. Matsumoto. 2020. Genome-wide identification of essential genes in Mycobacterium intracellulare by transposon sequencing - Implication for metabolic remodeling. Sci Rep 10: 5449.

 

Ozuru, R., S. Wakao, T. Tsuji, N. Ohara, T. Matsuba, M. Y. Amuran, J. Isobe, M. Iino, N. Nishida, S. Matsumoto, K. Iwadate, N. Konishi, K. Yasuda, K. Tashiro, M. Hida, A. Yadoiwa, S. Kato, E. Yamashita, S. Matsumoto, Y. Kurozawa, M. Dezawa, and J. Fujii. 2020. Rescue from Stx2-Producing E. coli-Associated Encephalopathy by Intravenous Injection of Muse Cells in NOD-SCID Mice. Mol Ther 28: 100-118.

 

Niki, M., T. Yoshiyama, H. Nagai, Y. Miyamoto, M. Niki, K. I. Oinuma, T. Tsubouchi, Y. Kaneko, S. Matsumoto, Y. Sasaki, and Y. Hoshino. 2020. Nutritional status positively impacts humoral immunity against its Mycobacterium tuberculosis, disease progression, and vaccine development. PLoS One 15: e0237062.

 

Hayashi, M*., A. Nishiyama*, R. Kitamoto, Y. Tateishi, M. Osada-Oka, Y. Nishiuchi, S. A. Kaboso, X. Chen, M. Fujiwara, Y. Inoue, Y. Kawano, M. Kawasaki, T. Abe, T. Sato, K. Kaneko, K. Itoh, S. Matsumoto, and M. Matsumoto. 2020. Adduct formation of delamanid with NAD in mycobacteria. Antimicrob Agents Chemother.

 

Yoshitaka Tateishi, Yusuke Minato, Anthony D. Baughn, Hiroaki Ohnishi, Akihito Nishiyama, Yuriko Ozeki, and Sohkichi Matsumoto

Genome-wide identification of essential genes in Mycobacterium intracellulare by transposon sequencing — Implication for metabolic remodeling, Sci Rep, Published: 25 March 2020

 

Mikayo Hayashi*, Akihito Nishiyama*, Ryuki Kitamoto, Yoshitaka Tateishi, Mayuko Osada-Oka, Yukiko Nishiuchi, Shaban A. Kaboso, Xiuhao Chen, Mamoru Fujiwara, Yusuke Inoue, Yoshikazu Kawano, Masanori Kawasaki, Tohru Abe, Tsutomu Sato, Kentaro Kaneko, Kimiko Ito, Sohkichi Matsumoto, and Makoto Matsumoto

Adduct formation of delamanid with NAD in mycobacteria

Antimicrob Agents Chemother, Published online March 9, 2020.

 

Yoshiro Yamashita, Toshiyuki Oe, Kenji Kawakami, Mayuko Osada-Oka, Yuriko Ozeki, Kazutaka Terahara, Ikkoh Yasuda1, Tansy Edwards, Takeshi Tanaka, Yasuko Tsunetsugu-Yokota, Sohkichi Matsumoto, Koya Ariyoshi

Non-Th1 type CD4+ T cell responses are preferentially induced by latency-associated Mycobacterium tuberculosis antigens in the state of latent M. tuberculosis infection

Frontiers in Immunology, 29 November 2019

 

Ryo Ozuru, Shohei Wakao, Takahiro Tuji, Naoya Ohara, Matsuba Takashi, Muhammad Y Amuran, Junko Isobe, Morio Iino, Naoki Nishida, Sari Matsumoto, Kimiharu Iwadate, Noriko Konishi, Kaori Yasuda, Kosuke Tashiro, Misato Hida, Arisato Yadoiwa, Shinsuke Kato, Eijiro Yamashita, Sohkichi Matsumoto, Yoichi Kurozawa, Mari Dezawa, Jun Fujii

Rescue from Shiga toxin 2-producing Escherichia coli-associated encephalopathy by intravenous injection of Muse cells in NOD-SCID mice. Molecular Therapy, In press, 2019.

 

Desak Nyoman Surya Suameitria Dewi, Ni Made Mertaniasih, Soedarsono, Yuriko Ozeki, Wayan Tunas Artama, Fihiruddin, Mamiko Niki, Yoshitaka Tateishi, Manabu Ato, & Sohkichi Matsumoto

Characteristic profile of antibody responses to PPD, ESAT-6, and CFP-10 of Mycobacterium tuberculosis in pulmonary tuberculosis suspected cases in Surabaya, Indonesia, Brazil J Infect Dis, Volume 23, Issue 4, July–August 2019, Pages 246-253

 

Osada-Oka, M., N. Goda, H. Saiga, M. Yamamoto, K. Takeda, Y. Ozeki, T. Yamaguchi, T. Soga, Y. Tateishi, K. Miura, D. Okuzaki, K. Kobayashi, and S. Matsumoto.

Metabolic adaptation to glycolysis is a basic defense mechanism of macrophages for Mycobacterium tuberculosis infection. International Immunology, Volume 31, Issue 12, December 2019, Pages 781–793,

 

Maekura, R., S. Kitada, M. Osada-Oka, Y. Tateishi, Y. Ozeki, T. Fujicawa, M. Miki, O. Jyunnko, M. Mori, and S. Matsumoto.

Serum antibody profiles in individuals with latent Mycobacterium tuberculosis infection. Microbiol Immunol 63: 130-138. 2019

 

 

Yukiko Ohara, Yuriko Ozeki, Yoshitaka Tateishi, Tsukasa Mashima, Fumio Arisaka, Yasuo Tsunaka, Yoshie Fujiwara, Akihito Nishiyama, Yutaka Yoshida, Kengo Kitadokoro, Haruka Kobayashi, Yukihiro Kaneko, Ichiro Nakagawa, Ryoji Maekura, Saburo Yamamoto, Masato Katahira & Sohkichi Matsumoto

Significance of a histone-like protein with its native structure for the diagnosis of asymptomatic tuberculosis.

PLOS ONE, August 27, 2021 https://doi.org/10.1371/journal.pone.0256946

 

Anna Savitskaya, Akihito Nishiyama, Takehiro Yamaguchi, Yoshitaka Tateishi, Yuriko Ozeki, Masaaki Nameta, Tomohiro Kon, Shaban A. Kaboso, Naoya Ohara, Olga V. Peryanova, and Sohkichi Matsumoto 

C-terminal intrinsically disordered region-dependent organization of the mycobacterial genome by a histone-like protein.

Scientific Reports. May29;8(1)8197, 2018

 

Manabu Inoue, Mamiko Niki, Yuriko Ozeki, Sachiyo Nagi, Evans Chadeka, Takehiro Yamaguchi, Mayuko Osada-Oka, Kenji Ono, Tetsuya Oda, Faith Mutungi, Yukihiro Kaneko, Makoto Matsumoto, Satoshi Kaneko, Yoshio Ichinose, Sammy M Njenga, Shinjiro Hamano, and Sohkichi Matsumoto.

High-density lipoprotein suppresses tumor necrosis factor alpha production by mycobacteria-infected human macrophages.

Scientific Reports, Apr 30;8(1);6736, 2018

 

 Niki M, Yoshiyama T, Miyamoto Y, Okamura M. Niki M, Oinuma K, Kaneko Y, Matsumoto S, Sasaki Y, Ogata H, Goto H, Kudoh S, and Hoshino Y.

Longgitudial evaluation of humoral immunity and bacterial and clinical parameters reveals that antige-specific antibodies suppress inflammatory responses in active tuberculosis.

J Immun Res, 4;2018:4928757, 2018

 

尾関　百合子、松本　壮吉. ｢結核免疫防御機能｣、特集；結核・非結核抗酸菌症（医学書院）、66巻、4号、p643-649、2018

 

松本　壮吉.  「抗酸菌感染症」、バイオフィルム感染症の診断・治療・予防 「臨床と微生物」 45巻、1号、P63-67、2018

 

松本　壮吉. 「マイコバクテリウム属、アクチノマイセスとノカルジア」「シンプル微生物学　改訂第６版」、小熊　恵二、堀田　博、若宮　伸隆　編.南江堂、東京、196-203、2018

 

 

Enany, S., Y. Yoshida, Y. Tateishi, Y. Ozeki, A. Nishiyama, A. Savitskaya, T. Yamaguchi, Y. Ohara, T. Yamamoto, M. Ato, and S. Matsumoto. 2017. Mycobacterial DNA-binding protein 1 is critical for long term survival of Mycobacterium smegmatis and simultaneously coordinates cellular functions. Scientific reports 7: 6810.

 

Totani, T., Y. Nishiuchi, Y. Tateishi, Y. Yoshida, H. Kitanaka, M. Niki, Y. Kaneko, and S. Matsumoto. 2017. Effects of nutritional and ambient oxygen condition on biofilm formation in Mycobacterium avium subsp. hominissuis via altered glycolipid expression. Scientific reports 7: 41775.

 

Chadeka, E. A., S. Nagi, T. Sunahara, N. B. Cheruiyot, F. Bahati, Y. Ozeki, M. Inoue, M. Osada-Oka, M. Okabe, Y. Hirayama, M. Changoma, K. Adachi, F. Mwende, M. Kikuchi, R. Nakamura, Y. D. J. Kalenda, S. Kaneko, K. Hirayama, M. Shimada, Y. Ichinose, S. M. Njenga, S. Matsumoto, and S. Hamano. 2017. Spatial distribution and risk factors of Schistosoma haematobium and hookworm infections among schoolchildren in Kwale, Kenya. PLoS Negl Trop Dis 11: e0005872.

 

松本　壮吉. 結核の潜在化と発症機構　「結核　改訂版」　光山　正雄、鈴木　克洋　編.医薬ジャーナル社、大阪、134-149、2017

 

 

Totani, T., Y. Nishiuchi, Y. Tateishi, Y. Yoshida, H. Kitanaka, M. Niki, Y. Kaneko, and S. Matsumoto. 2017. Effects of nutritional and ambient oxygen condition on biofilm formation in Mycobacterium avium subsp. hominissuis via altered glycolipid expression. Sci, Rep 2045-2322 (Electronic).

 

Takahashi, H., M. Haga, T. Sunagawa, T. Saitoh, T. Kitahara, S. Matsumoto, and M. Ohnishi. 2016. Meningococcal carriage rates in healthy individuals in Japan determined using Loop-Mediated Isothermal Amplification and oral throat wash specimens. Journal of infection and chemotherapy : 22: 501-504.

 

 

Niki, M., M. Suzukawa, S. Akashi, H. Nagai, K. Ohta, M. Inoue, M. Niki, Y. Kaneko, K. Morimoto, A. Kurashima, S. Kitada, S. Matsumoto, K. Suzuki, and Y. Hoshino. 2015. Evaluation of Humoral Immunity to Mycobacterium tuberculosis-Specific Antigens for Correlation with Clinical Status and Effective Vaccine Development. J Immunol Res: aa527395.

 

Ozeki, Y., M. Igarashi, M. Doe, A. Tamaru, N. Kinoshita, Y. Ogura, T. Iwamoto, R. Sawa, M. Umekita, S. Enany, Y. Nishiuchi, M. Osada-Oka, T. Hayashi, M. Niki, Y. Tateishi, M. Hatano, and S. Matsumoto. 2015. A New Screen for Tuberculosis Drug Candidates Utilizing a Luciferase-Expressing Recombinant Mycobacterium bovis Bacillus Calmette-Gueren. PLoS One 10: e0141658.

 

Takahashi, H., M. Haga, T. Sunagawa, T. Saitoh, T. Kitahara, S. Matsumoto, and M. Ohnishi. 2016. Meningococcal carriage rates in healthy individuals in Japan determined using Loop-Mediated Isothermal Amplification and oral throat wash specimens. Journal of infection and chemotherapy.  In press 

 

松本　壮吉、西山　晃史、尾関　百合子。結核菌の潜伏感染に関わるメカニズムと新しい結核制御技術の可能性。化学療法の領域。31 巻、9号、ｐ93-100、2015

 

松本　壮吉、結核菌の増殖制御や潜在性結核の解析および、結核ワクチンの開発研究。臨床と研究　別刷。92巻、p116、2015

 

立石　善隆、松本　壮吉。結核菌の病原因子。呼吸器内科。29巻、1号、p65-70、2016

 

 

Nishiuchi, Y., A. Tamaru, Y. Suzuki, S. Kitada, R. Maekura, Y. Tateishi, M. Niki, H. Ogura, and S. Matsumoto. 2014. Direct detection of Mycobacterium avium in environmental water and scale samples by loop-mediated isothermal amplification. J Water Health 12:211-219.

 

Nagi, S., E. A. Chadeka, T. Matsumoto, S. and S. Hamano等 2014. Risk Factors and Spatial Distribution of Schistosoma mansoni Infection among Primary School Children in Mbita District, Western Kenya. PLoS Negl Trop Dis 8:e2991.

 

Fujii, Y., S. Kaneko, S. M. Nzou, S. Matsumoto 等. 2014. Serological surveillance development for tropical infectious diseases using simultaneous microsphere-based multiplex assays and finite mixture models. PLoS Negl Trop Dis 8:e3040.

 

Ohtsuka, K., H. Ohnishi, E. Nozaki, J. Pais Ramos, E. Tortoli, S. Yonetani, S. Matsushima, Y. Tateishi, S. Matsumoto, and T. Watanabe. 2014. Whole-Genome Sequence of Mycobacterium kyorinense. Genome Announc 2:e01062-01014.

 

Morimoto, K., T. Ozawa, K. Awazu, N. Ito, N. Honda, S. Matsumoto, and D. Tsuruta. 2014. Photodynamic Therapy Using Systemic Administration of 5-Aminolevulinic Acid and a 410-nm Wavelength Light-Emitting Diode for Methicillin-Resistant Staphylococcus aureus-Infected Ulcers in Mice. PLoS One 9:e105173.

 

松本　壮吉、尾関　百合子。結核ワクチン開発の現状と新しい結核ワクチン開発に向けて。化学療法の領域。30巻、p127-134, 2014.  

 

西内　由紀子、松本　壮吉。抗酸菌の細菌学的特徴と病原性。感染症内科.　2巻、p8-14, 2014

 

松本　壮吉。　結核とその制圧を目指した研究。新潟県医師会報.　第766号.　P2-7, 2014

 

西山　晃史、松本　壮吉。病原微生物学、荒川　宣親、神谷　茂、柳　雄介　監修、抗酸菌と放線菌。東京化学同人、東京。120-129、2014

 

 

Osada-Oka, M., Y. Tateishi, Y. Hirayama, Y. Ozeki, M. Niki, S. Kitada, R. Maekura, K. Tsujimura, Y. Koide, N. Ohara, T. Yamamoto, K. Kobayashi, and S. Matsumoto. 2013. Antigen 85A and mycobacterial DNA-binding protein 1 are targets of immunoglobulin G in individuals with past tuberculosis. Microbiol Immunol 57:30-37.

 

Tateishi, Y., A. Tamaru, Y. Ogura, M. Niki, T. Wada, T. Yamamoto, K. Hirata, T. Hayashi, and S. Matsumoto. 2013. Whole-Genome Sequence of the Potentially Hypertransmissible Multidrug-Resistant Mycobacterium tuberculosis Beijing Strain OM-V02_005. Genome Announc 1.

 

amashita, Y., Y. Hoshino, M. Oka, S. Matsumoto, H. Ariga, H. Nagai, M. Makino, K. Ariyoshi, and Y. Tsunetsugu-Yokota. 2013. Multicolor Flow Cytometric Analyses of CD4(+) T Cell Responses to Mycobacterium tuberculosis-Related Latent Antigens. Jpn J Infect Dis 66:207-215.

 

Taniguchi, K., T. Takii, S. Yamamoto, J. Maeyama, S. Iho, M. Maruyama, N. Iizuka, Y. Ozeki, S. Matsumoto, T. Hasegawa, Y. Miyatake, S. Itoh, and K. Onozaki. 2013. Reactivation of immune responses against Mycobacterium tuberculosis by boosting with the CpG oligomer in aged mice primarily vaccinated with Mycobacterium bovis BCG. Immun Ageing 10:25.

 

Fukuda, T., T. Matsumura, M. Ato, M. Hamasaki, Y. Nishiuchi, Y. Murakami, Y. Maeda, T. Yoshimori, S. Matsumoto, K. Kobayashi, T. Kinoshita, and Y. S. Morita. 2013. Critical roles for lipomannan and lipoarabinomannan in cell wall integrity of mycobacteria and pathogenesis of tuberculosis. MBio 4:e00472-00412.

 

松本　壮吉。潜在性結核と結核菌の潜伏感染メカニズム. 医学のあゆみ 246, p470-473, 2013.  

 

松本　壮吉。抗酸菌の休眠現象や薬剤抵抗性に関わる分子メカニズム. Jpn. J. Lepr., 82, p119-122, 2013.  

 

仁木　満美子、松本　壮吉、鉄代謝およびイソニアジド耐性にかかわる結核菌分子の機能と治療法開発の可能性。化学療法の領域、Vol29  2号、p119-124．2013.

 

 

Niki, M., M. Niki, Y. Tateishi, Y. Ozeki, T. Kirikae, A. Lewin, Y. Inoue, M. Matsumoto, J. L. Dahl, H. Ogura, K. Kobayashi, and S. Matsumoto. 2012. A novel mechanism of growth phase-dependent tolerance to isoniazid in mycobacteria. J Biol Chem 287:27743-27752.

 

ateishi, Y., S. Kitada, K. Miki, R. Maekura, Y. Ogura, Y. Ozeki, Y. Nishiuchi, M. Niki, T. Hayashi, K. Hirata, K. Kobayashi, and S. Matsumoto. 2012. Whole-Genome Sequence of the Hypervirulent Clinical Strain Mycobacterium intracellulare M.i.198. J Bacteriol 194:6336.

 

Tamaru, A., C. Nakajima, T. Wada, Y. Wang, M. Inoue, R. Kawahara, R. Maekura, Y. Ozeki, H. Ogura, K. Kobayashi, Y. Suzuki, and S. Matsumoto. 2012. Dominant Incidence of Multidrug and Extensively Drug-Resistant Specific Mycobacterium tuberculosis Clones in Osaka Prefecture, Japan. PLoS One 7:e42505.

 

Fujii, J., M. Naito, T. Yutsudo, S. Matsumoto, D. P. Heatherly, T. Yamada, H. Kobayashi, S. Yoshida, and T. Obrig. 2012. Protection by a Recombinant Mycobacterium bovis Bacillus Calmette-Guerin Vaccine Expressing Shiga Toxin 2 B Subunit against Shiga Toxin-Producing Escherichia coli in Mice. Clin Vaccine Immunol 19:1932-1937.

 

松本　壮吉、結核菌の増殖、長期生存、および静止期以降の薬剤抵抗性獲得の分子メカニズム、Bacterial Adherence & Biofilm、Vol. 26, p21-24,